上海金畔生物代理jena品牌蛋白结晶试剂耗材工具等，我们将竭诚为您服务，欢迎访问jena官网或者咨询我们获取更多相关jena品牌产品信息。
- Get started
- Screening
- Screening Membrane Proteins
- Optimization
- Data Collection
- Phasing
- Cryo-EM
- Cryo-EM V-Kit
- Quantifoil® Holey Carbon Films
- Quantifoil® Holey Carbon Films with 2 nm Continuous Carbon
- UltrAuFoil® Holey Gold Films
- Other Quantifoil® Films
- C-flat™ Holey Carbon Films
- Au-flat™ Holey Gold Films
- Amphipol A8-35
- Specimen Storage and Shipping
Quantifoil® Holey Carbon Films
Quantifoil® is a holey carbon film with a thickness of about 12 nm, that is applied on a standard copper or gold electron microscopy grid and provides an ideal support for biological samples in cryo-EM techniques[1-8].
The supporting mesh (copper or gold) is available with distinct numbers. Higher mesh numbers (400) indicate closely spaced bars and provide higher stability, whereas lower numbers (200) provide larger free faces.
The Quantifoil® carbon film has circular holes of defined size and interspace, e.g. R 2/1 (pictured) has holes of 2 µm diameter with an interspace of 1 µm in both dimensions. Higher magnifications usually require smaller holes and vice versa.
You have the following options to choose from:
Quantifoil® film
- R 0.6/1 (0.6 µm hole diameter/1 µm interspace)
- R 1.2/1.3 (1.2 µm hole diameter/1.3 µm interspace)
- R 2/1 (2 µm hole diameter/1 µm interspace)
- R 2/2 (2 µm hole diameter/2 µm interspace)
- R 3.5/1 (3.5 µm hole diameter/1 µm interspace)
Supporting mesh material
- Copper
- Gold
Supporting mesh number
- 200
- 300
- 400
Products & Ordering
Selected Recent Literature Citations of Quantifoil®
[1] Lee et al. (2019) Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation. Cell Reports 26:29.
[2] Azubel et al. (2019) FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles. eLife DOI:10.7554/eLife.43146.
[3] Zhao et al. (2018) Structure and mechanogating mechanism of the Piezo1 channel. Nature 554:487.
[4] Wijnands et al. (2018) Controlling protein activity by dynamic recruitmenton a supramolecular polymer platform. Nat. Commun. 9:65.
[5] Ke et al. (2018) Promotion of virus assembly and organization by the measles virus matrix protein. Nat. Commun. 9:1736.
[6] Zhang et al. (2018) Molecular structure of the ATP-bound, phosphorylated human CFTR. PNAS 115:12757.
[7] Park et al. (2017) Structure of a CLC chloride ion channel by cryo-electron microscopy. Nature 541:500.
[8] Ekiert et al. (2017) Architectures of Lipid Transport Systems for the Bacterial Outer Membrane. Cell 169:273.