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Products > Crystallization Plates, Hardware & Accessories > Sealing Films, Tapes, Mats & Covers > Hanging Drop Seal

Hanging Drop Seal

Applications

Hanging drop vapor diffusion
96 round wells

Features

ANSI/SLAS 1-2004 Standard
Accommodates 3 separate drops of protein per well
Fits standard 2 or 3 drop MRC plates
Fits Greiner 655101 microplate (Hampton Research HR3-139)
100 micron thickness
Choice of UVP compatible or non-UVP compatible material

Description

The Hanging Drop Seal is compatible with the 96 Well Clear Polystyrene Flat Bottom Microplate by Griener Bio One.

The revolutionary SWISSCI Hanging Drop Seal (UVOP / Non-UVP) comes ready to use with a dust-free protective coating and specialty polymer base. The Seals accommodate up to 3 separate drops of protein and fit the standard 2-drop or 3-drop MRC plates as well as Greiner 655101 microplate (Hampton Research HR3-139). The product has a 100 micron thin layer of UVP specialty polymer developed for compact drop creation and ability to shoot X-ray without any noticeable diffraction. The non-UVP seal comes in 100-micron layer.

The SWISSCI hanging drop seals can be run with individual drops in the 96 positions or 192 drops – or 288 drops. The volume of the drop is typically between 50 and 100 nanolitres. The seal covers sit directly over the microwell plate crystallization reagent wells and are closed with a long term resistant closing adhesive which is validated not to ingress into the sample, nor lead to seal corruption.

To remove an individual crystal the seal may be peeled back or simply cut out with a knife. The material is very thin although still remaining as a perfect evaporation barrier and can be sliced with a knife very easily.

The seals are produced in a class 100,000 cleanroom environment and are dust and scratch-free. Optical quality is of the highest level available. The seals are able to be used in the UV / Non-UVP range thus enabling the user to recognize salt – from protein crystals under a UV source microscope.