beMatrix Series
Biomedical Research & Treatments
The past decade has seen major advances in the biomedical field, specifically in stem-cell research, regenerative medicine and transplantation. In response, cell therapy and gene therapy products are evolving at a corresponding pace. Nitta Gelatin’s beMatrix™ low endotoxin gelatin and collagen are specifically designed to meet the most stringent safety and quality specifications required for emerging biomedical applications. In addition to setting the industry gold-standard for low endotoxin levels, beMatrix™ Gelatin and Collagen are also sterilized using a proprietary method for the control of bacteria and viruses.
New techniques to combine cells with low endotoxin gelatin or collagen are leading the way in biomedical research and development. Recently, beMatrix™ Collagen AT was chosen as the material for a retinal pigment epithelial sheet in the first human clinical study based on iPS cells. In the field of regenerative medicine, beMatrix™ Gelatin was successfully used as the scaffolding material for the in-growth of new bone for osteoconductive implants.
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beMatrix™ Gelatin
beMatrix™ Gelatin products are created using proprietary technology to yield unmatched safety and quality. Controlled for exceptionally low endotoxin levels and enhanced purity, beMatrix™ products are well suited for a range of biomedical applications including drug excipient, wound dressing materials, bone void fillers, and more.
Features
- Low endotoxin level: NMT 10 EU/g
- Virus inactivated
- IPEC-PQG GMP Compliant
- USP / EP (Ph. Eur.) / JP Compliant
- DMF / MAF registered
- Storage Condition: Room temperature
- Expiration date: 3 years from date of manufacture
- Safety Test performed
Test Item Cytotoxicity Sensitization Intradermal Reaction Pyrogen Antigenicity Result Negative Negative Negative Negative Negative
beMatrix™ Gelatin LS-H
Features
- Alkaline-treated gelatin derived from porcine skin
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High Gel Strength (about 300g)
beMatrix™ Gelatin LS-250
Features
- Sterilized alkaline-treated gelatin derived from porcine skin
- High Gel Strength (about 250g)
- Designed for higher density and faster gelation
beMatrix™ Gelatin LS-W
Features
- Alkaline-treated gelatin derived from porcine skin
- Low Gel Strength (about 100g)
beMatrix™ Gelatin HG
Features
- Sterilized gelatin hydrolyzate derived from porcine skin
- Acute Systemic Toxicity: Negative
- Subacute Toxicity: Negative
beMatrix™ Collagen
The first collagen product used in the world’s first iPS cells based transplant.
beMatrix™ Collagen was used for culturing retinal cells derived from iPS cells that were used for treatment of “age-related macular degeneration”. Cultured cells were successfully transplant in patient without canceration, becoming the world first case.
beMatrix™ Collagen is High quality collagen with strict endotoxin control and virus inactivating processing.
beMatrix™ Collagen AT
Features
- Acid extracted collagen solution derived from porcine tendon
- Low endotoxin level: NMT 0.5 EU/mL
- Storage Condition: Cold storage [4 °C to 8 °C]
- Expiration date: 2 years from the date of manufacture
- Concentration: 3 mg/mL, pH 3
beMatrix™ Collagen TE
Features
- Pepsin-solubilized collagen solution derived from porcine skin
- Low endotoxin level: NMT 0.5 EU/mL
- Storage Condition: Cold storage [4 °C to 8 °C]
- Expiration date: 2 years from the date of manufacture
- Concentration: 5 mg/mL, pH 3
beMatrix™ Collagen FD
Features
- Freeze-dried atelocollagen derived from porcine skin
- Low endotoxin level: NMT 100 EU/g
- Storage Condition: Room temperature
- Expiration date: 2 years from the date of manufacture
Product Appearance
- Spongiform
- Size: approx. 140 x 100 x 10 mm
Application
- Scaffold
- Cell culture / transplantation
- Electro-spinning etc.
agement and virus inactivating processing.
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Low Endotoxin Gelatin
Low Endotoxin Collagen
Other Products of Nitta Gelatin
Related Information
Category
- Cell Culture
- Animal Cell Culture
- Biomaterial
- Cell Culture
- Stem Cell Culture
- Extracellular Matrix / Cell Coating
- Cell Culture
- Cell Culture Plasticware
- Extracellular Matrix / Cell Coating
- Pharma Manufacturing & QC
- Raw Material
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